There are flights to the Maldives direct from Europe as well as via the Middle East and from the main Asian airports with connections from the USA or Australia. Some airlines only operate seasonal charters and some have a code-sharing arrangement with other carriers flying to Velana International Airport.
Domestic airports are at:
If your resort requires a seaplane transfer, a few things to be aware of: the seaplanes only operate in daylight hours, so if you arrive after sunset you'll have to stay in Male overnight before being able to transfer to your resort. Ditto if your flight home is early in the morning - you will leave your resort the afternoon before - make sure you check with your tour operator that you will be given accommodation while you wait for your international flight.
The seaplane journey in itself is an experience, as you get stunning views of the atolls - make sure you get a window seat and that you get your camera out before boarding (your hand luggage will probably be put at the back of the plane as there's no space under or over the seats). The seaplane will usually land next to a floating platform, from which you will be picked up by boat to be taken the remaining few meters inshore to your resort.
Some resorts have landing stages that allow the seaplane to deliver you right up to the beaches of your destined resorts. It is an amazing feeling to get off the seaplane & right on to the sunny white beaches of the country where waves are sweeping at your feet. NB - seaplane transfer methods vary from resort to resort.